A Drug-Coated Balloon Prevents Target Lesion Failures in High-Risk Patients


Angioplasty with a drug-coated balloon helps to prevent target lesion failure in patients who are at high risk for coronary artery in-stent restenosis. It is superior to traditional balloon angioplasty to treat coronary artery in-stent restenosis. According to recent clinical trials, it helped achieve a 50% reduction in target lesion restenosis. It also recorded a 50% reduction in target vessel MI (myocardial infarction). So, it is better than conventional angioplasty.

Robert Yeh, MD, who works at Boston-based Beth Israel Deaconess Medical Center, said the target lesion failure rate was just 28.7% in patients who were subjected to a balloon angioplasty treatment. The rate of target lesions was 17.9% in patients cured with an AGENT paclitaxel-coated balloon. So, the drug-coated balloon posted a 38% relative risk reduction and a 10% absolute risk reduction at the endpoint.

According to information from healthcare experts at Medriva, in-stent restenosis accounted for 10% of the overall percutaneous coronary interventions. These patients may have several layers, and it could be a fourth or third layer, which the surgeons try to avoid.

Approval is pending for drug-coated balloons in the US

Drug-coated balloons are yet to receive the nod from regulators in the US. It can deliver drugs that prevent the formation of blockages. These devices are already available in Japan and Europe. The technical success rate for the AGENT DCB group is 92.9%, compared to 89.3% for those treated with balloon angioplasty. DCB helped to halve the rate of target vessel MI and target lesion revascularization compared to conventional angioplasty. It is considered superior to other measures of clinical study outcomes.

Why does a patient need angioplasty?

Balloon angioplasty, also called angioplasty, is a procedure in which arteries are opened to allow the easy flow of blood. The healthcare providers at Medriva use balloon angioplasty, a minimally invasive procedure, in tight spots in the arteries. It is the place where plaque buildup inside the arteries blocks or narrows them.

Coronary angioplasty is recommended for patients with a heart attack or coronary artery disease. It is also used for patients in other parts of their body where the arteries are blocked or narrowed in areas like the kidneys, arms, pelvis, legs, and neck. The procedure of angioplasty allows the pumping of more blood through arteries that are either blocked or narrowed because of plaque. It ensures a better supply of blood to the organs in your body.

Angioplasty cures atherosclerosis

Atherosclerosis is a collection of plaque formed using cholesterol and fat in the arteries. So, the plaque blocks or narrows the arteries in sensitive areas of your body, obstructing the blood flow to organs.

People who are at risk of a heart attack or suffering from chest pain are treated with coronary angioplasty. It is helpful to widen the narrowed arteries or open the blocked arteries so that your heart receives sufficient oxygen. So, coronary angioplasty is used for the treatment of coronary artery disease.

Angioplasty is also used to treat atherosclerosis in the pelvis, legs, and arms. It also offers treatment for chronic kidney disease and carotid artery disease.


Many people are suffering from coronary artery disease because of unhealthy eating, physical inactivity, and smoking tobacco. As a result, your heart will not get enough nutrients, oxygen, and blood. So, the use of angioplasty with a drug-coated balloon improves your chances of survival. It is also necessary to make changes in eating patterns and engage in regular physical activity.

Subscribe to our magazine

━ more like this

Metallic Mastery: Unveiling the Strength of Stainless Steel Crowns

In the world of dentistry, stainless steel crowns stand out as a testament to the mastery of metallurgy in addressing a myriad of dental...

Probiotic Supplements for Young Teens: A Path to Better Health

Adolescence is a critical time for growth and development, thus it's critical to keep yourself healthy throughout this phase. The potential benefits of probiotic...

Apple Cider Vinegar: Your New Go-To for Natural Face Moisturization

Introduction Apple Cider Vinegar (ACV) has gained immense popularity in the realm of natural skincare. Praised for its versatility, ACV is not just a kitchen...

Can You Really Prevent Dental Cavities? Find Out the Symptoms and Possible Solutions!

Most people suffer from a cavity at some point in their lives, and in order to truly find out the proper ways to prevent...

Mouth Freshener FTT by Pass Pass

We've all been there in a situation where our breath isn't as fresh as we'd like it to be. Whether it's after a meal,...